Surgical management of advanced pelvic cancer

• Autore: Winter Desmond C
• Pubblicazione: Newark : , : John Wiley & Sons, Incorporated, , 2021; ©2022
• Descrizione fisica: 1 online resource (319 pages)
• Disciplina: 616.99/435059
• Soggetto topico: Pelvis - Cancer - Surgery; Pelvis - Cancer - Treatment
• Soggetto non controllato: Internal Medicine; Medical
• Altri autori: KellyMichael E
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: Cover -- Title Page -- Copyright Page -- Contents -- List of Contributors -- Preface -- Chapter 1 From Early Pioneers to the PelvEx Collaborative -- Background -- The Pioneers -- Brunschwig's Operation -- Urinary Reconstruction -- The Koenig-Rutzen Bag -- Evolution of the Uretero-Ileal Conduit -- Subspecialization and Partial Exenteration -- Composite Pelvic Exenterations -- Lateral Pelvic Sidewall Resection -- Future Directions -- References -- Chapter 2 The Role of the Multidisciplinary Team in the Management of Locally Advanced and Recurrent Rectal Cancer -- Background -- Complex Pelvic Cancer MDTM -- Staging, Restaging, and Pathological Assessment -- Staging -- Restaging -- Pathological Assessment -- Complex Cancer MDTM Outcomes -- References -- Chapter 3 Preoperative Assessment of Tumor Anatomy and Surgical Resectability -- Background -- Cancer Anatomy and Resectability -- Radiological Assessment of Cancer Anatomy by MRI -- Case Study -- Radiological Assessment of Metastatic Disease -- References -- Chapter 4 Neoadjuvant Therapy Options for Advanced Rectal Cancer -- Background -- Potential Advantages of TNT -- Potential Disadvantages of TNT -- Short-Term Outcomes -- Pathological Response -- Long-Term Oncological Outcomes -- Organ Preservation -- Chemotherapy and Compliance -- Novel Chemotherapeutic Agents -- Immunotherapeutics -- Locally Recurrent Rectal Cancer -- Future Developments -- References -- Chapter 5 Preoperative Optimization Prior to Exenteration -- Background -- Clinical Examination -- Laboratory Tests -- Risk Assessment of Morbidity and Mortality -- Preoperative Optimization -- Anemia Management -- Optimization of Nutritional Status -- Mechanical Bowel Preparation and Oral Antibiotic Prophylaxis -- Thromboprophylaxis -- Stoma Education -- References -- Chapter 6 Patient Positioning and Surgical Technology -- Background. ; Operating Room Setup -- General Room Setup -- Adjuncts to Operating Room Setup -- Robotic Room Setup -- Patient Positioning -- Modified Lloyd-Davies -- Jackknife Prone -- Complications Associated with Patient Positioning -- Surgical Equipment and Energy Devices -- References -- Chapter 7 Intraoperative Assessment of Resectability and Operative Strategy -- Background -- The Preoperative Phase -- Planning -- The Intraoperative Stage -- External Examination -- General Laparotomy -- References -- Chapter 8 Anterior Pelvic Exenteration -- Background -- Diagnostics Specific to Anterior Pelvic Exenteration -- Surgical Procedure -- Anesthesia and Starting the Procedure -- Urological Approach -- Gynecological Approach -- Rectal Cancer -- Ureter Dissection -- Lateral Compartment -- Partial Cystectomy -- Partial Prostatectomy -- Uterus and Vaginal Wall -- Urinary Diversion (Ileal Conduit) -- Urinary Diversion (Colon Conduit) -- Morbidity and Mortality -- Morbidity -- Mortality -- Complications -- Survival -- Quality of Life Following Anterior Pelvic Exenteration -- Sexual Dysfunction -- Urinary Dysfunction -- General and Mental Health -- References -- Chapter 9 Posterior Pelvic Exenteration -- Background -- Preoperative Assessment -- Intraoperative Decision-Making -- Surgical Technique -- References -- Chapter 10 Total Pelvic Exenteration -- Background -- Indications -- Who Should Be Performing these Procedures? Selecting the Right Team and Plan -- Specialist Centers -- Getting Patients Right - Fitness for Surgery (Prehabilitation) -- Preoperative Planning -- Examination under Anesthesia/Flexible Sigmoidoscopy/Colonoscopy -- Neoadjuvant Therapy -- Surgical Technique -- Uterus and Vagina Involvement -- Anterior Recurrences: Beyond the Normal Planes -- Posterior Compartment and Extended Bony Resections -- Lateral Pelvic Recurrences. ; Intraoperative Radiation Therapy -- Reconstruction -- Adjuncts to Care: Urinary and Sexual Function and Ostomy Placement -- References -- Chapter 11 Extended Exenterative Resections Involving Bone -- Background -- Anatomical Considerations -- Sacral Resection -- High Sacrectomy (S1/S2) Versus Low Sacrectomy (S3 and Below) -- Anterior Pubic Resection -- Lateral Pelvic Resection -- Patient Workup Specific to Bony Resection -- History and Examination -- Radiology -- Anesthetic Assessment -- Multidisciplinary Meeting -- Neoadjuvant treatment -- Operative Technique -- Surgical Approach -- Technique for Sacrectomy -- Reconstruction -- Intraoperative Radiotherapy -- Novel Approaches in Sacrectomy -- Partial Anterior Sacrectomy -- Laparoscopic Sacrectomy -- Outcomes -- References -- Chapter 12 Exenterative Resections Involving Vascular and Pelvic Sidewall Structures -- Background -- Anatomy -- Vascular -- Neurologic -- Urologic and Gynecologic -- Muscular -- Preoperative Evaluation -- Imaging -- Functional Status -- Informed Consent -- Intraoperative Management -- Preparation and Positioning -- Equipment -- Operative Approach -- Postoperative Management -- Complications -- References -- Chapter 13 Extended Exenterative Resections for Recurrent Neoplasm -- Background -- Strategies for Tackling Involvement of Posterior Compartment Including Sacrum -- Low Sacrectomy -- High Sacrectomy -- Perineal Closure -- Strategies for Tackling Involvement of Pelvic Sidewall -- Strategies for Tackling Involvement of Anterior Compartment -- References -- Chapter 14 Pelvic Exenteration in the Setting of Peritoneal Disease -- Background -- Treatment Options of Colorectal Peritoneal Metastases -- Pelvic Exenteration, Cytoreductive Surgery, and HIPEC -- References -- Chapter 15 Minimally Invasive Pelvic Exenteration -- Background. ; History of Minimally Invasive Pelvic Exenterative Surgery -- Rectal Cancer Beyond TME -- Advantages of a Robotic Approach to Exenteration -- Surgical Planning and Reconstruction -- Patient Factors -- Disease Factors -- Technical Factors -- Robotic Surgical Approach -- Outcomes -- Future Directions -- Summary Box -- References -- Chapter 16 Stoma Considerations Following Exenteration -- Background -- Urinary Diversion -- Incontinent Urinary Diversions -- Ileal Conduit -- Transverse Colon Urinary Diversion -- Distal Colon Urinary Diversion -- Direct Cutaneous Ureterostomy -- Continent Urinary Diversions -- Miami Pouch -- Indiana Pouch -- Uretero-ileocecal Appendicostomy -- Orthotopic Neobladder -- Comparison of Continent and Incontinent Urinary Diversions -- Urological Leaks -- Fecal Diversion -- Combined Fecal and Urinary Diversion -- Wet Colostomy -- Double-Barreled Wet Colostomy -- Parastomal Hernia -- Future Developments -- References -- Chapter 17 Reconstructive Techniques Following Pelvic Exenteration -- Background -- Bowel Reconstruction -- Options -- Urinary Tract Reconstruction -- Ureteric Reimplantation -- Urinary Diversion, Conduit, and Uretostomy -- Reconstruction of Perineum -- Omentum -- Mesh -- Pedicle Flaps -- Fasciocutaneous Flaps -- Myocutaneous Flaps and Free Flaps -- References -- Chapter 18 Minimizing Morbidity from Pelvic Exenteration -- Background -- Knowing the Risks -- Intraoperative Management -- General Considerations -- Surgical Considerations -- Preoperative Considerations -- Intraoperative Considerations -- Postoperative Management -- Critical Care -- Venous Thromboembolic Prophylaxis -- Enhanced Recovery after Surgery -- Postoperative Complications -- Early Complications -- Long-Term Complications -- References -- Chapter 19 Crisis Management -- Background -- Prior to Surgery -- Intraoperative Management. ; Hemorrhage Control -- Postoperative Hemorrhage -- Nerve Damage -- Obturator Nerve -- Femoral Nerve -- Sciatic Nerve -- Sacralplexus -- Injury to Bowel or Urinary Tract -- Postoperative Management -- Abdominal Compartment -- Delayed Presentation of Bowel or Urinary Tract Injury -- Massive Transfusion -- References -- Chapter 20 Quality of Life and Patient-Reported Outcome Measures Following Pelvic Exenteration -- Background -- Quality of Life and Patient-Reported Outcomes Instruments -- Quality of Life Trajectories Following Pelvic Exenteration -- Gynecological Malignancies -- Rectal Malignancy -- Mixed Malignancies -- Palliative Exenteration -- Predictors of Postoperative Quality of Life -- Patient-Reported Outcome Measures Following Pelvic Exenteration -- Future Directions -- References -- Chapter 21 Adjuvant Therapy options after Pelvic Exenteration for Advanced Rectal Cancer -- Background -- Adjuvant Therapy -- Novel Agents -- Radiotherapy -- Future Directions -- References -- Chapter 22 Adjuvant Therapy Options after Pelvic Exenteration for Gynecological Malignancy -- Background -- Cervical Cancer -- Vaginal Cancer -- Vulval Cancer -- Endometrial Cancer -- Ovarian Cancer -- References -- Chapter 23 Adjuvant Therapy Options for Urological Neoplasms -- Background -- Prostate Cancer -- Radiation Therapy -- Brachytherapy -- Hormonal Therapy: Gonadotropin-Releasing Hormone (GnRH) Analogs -- Abiraterone Acetate -- Enzalutamide -- Chemotherapy -- Second-line Treatment for Metastatic Prostate Cancer -- Bladder Cancer -- Chemotherapy -- Immunotherapy -- Radiotherapy -- Conclusion -- References -- Chapter 24 The Role of Re-irradiation for Locally Recurrent Rectal Cancer -- Background -- Treatment of Locally Recurrent Rectal Cancer -- Morbidity After Re-irradiation -- Primary Outcome after Re-irradiation for LRRC -- References. ; Chapter 25 Palliative Pelvic Exenteration.
• Sommario/riassunto: "For many patients with locally advanced primary or locally recurrent pelvic malignancy, pelvic exenteration (PE), involving radical multivisceral resection of the pelvic organs, represents the best treatment option. The first report of PE was in 1948 by Alexander Brunschwig of the Memorial Hospital (New York City, USA), as a palliative procedure for cervical cancer. 1 Due to high morbidity and mortality rates many considered palliative exenteration too radical, and initially it was performed only in a small number of centers in North America.2 Technologic advancements, surgical innovations and improved perioperative care facilitated the evolution of safer and more radical exenterative techniques for the treatment of advanced gastrointestinal and urogynaecological malignancies.3 Worldwide collaborative data 4, 5 have demonstrated that a negative resection margin is crucial in predicting survival and quality of life after surgery. Carefully selected patients who undergo en-bloc resection of all contiguously involved anatomic structures with R0 resection margins can now expect good long-term survival with acceptable levels of morbidity. 4, 5"--
• Altri titoli varianti: Surgical Management of Advanced Rectal Cancers
• Titolo autorizzato: Surgical management of advanced pelvic cancer
• ISBN: 1-119-51841-5; 1-119-51849-0
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910840832903321
• Lo trovi qui: Univ. Federico II